Hip1-related Mutant Mice Grow and Develop Normally but Have Accelerated Spinal Abnormalities and Dwarfism in the Absence of HIP1

In mice and humans, there are two known members of the Huntingtin interacting protein 1 (HIP1) family, HIP1 and HIP1-related (HIP1r). Based on structural and functional data, these proteins participate in the clathrin trafficking network. The inactivation of Hip1 in mice leads to spinal, hematopoiet...

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Hlavní autoři: Hyun, Teresa S., Li, Lina, Oravecz-Wilson, Katherine I., Bradley, Sarah V., Provot, Melissa M., Munaco, Anthony J., Mizukami, Ikuko F., Sun, Hanshi, Ross, Theodora S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC400480/
https://ncbi.nlm.nih.gov/pubmed/15121852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4329-4340.2004
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