Functional but Abnormal Adult Erythropoiesis in the Absence of the Stem Cell Leukemia Gene

Previous studies have indicated that the stem cell leukemia gene (SCL) is essential for both embryonic and adult erythropoiesis. We have examined erythropoiesis in conditional SCL knockout mice for at least 6 months after loss of SCL function and report that SCL was important but not essential for t...

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Detalhes bibliográficos
Main Authors: Hall, Mark A., Slater, Nicholas J., Begley, C. Glenn, Salmon, Jessica M., Van Stekelenburg, Leonie J., McCormack, Matthew P., Jane, Stephen M., Curtis, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190361/
https://ncbi.nlm.nih.gov/pubmed/16024775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6355-6362.2005
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