Abnormal Cardiac Development in the Absence of Heart Glycogen

Glycogen serves as a repository of glucose in many mammalian tissues. Mice lacking this glucose reserve in muscle, heart, and several other tissues were generated by disruption of the GYS1 gene, which encodes an isoform of glycogen synthase. Crossing mice heterozygous for the GYS1 disruption resulte...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Pederson, Bartholomew A., Chen, Hanying, Schroeder, Jill M., Shou, Weinian, DePaoli-Roach, Anna A., Roach, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.7179-7187.2004
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