Thioredoxin-Interacting Protein Stimulates Its Own Expression via a Positive Feedback Loop

Thioredoxin-interacting protein (TXNIP) has emerged as a key regulator of important cellular processes including redox state, inflammation, and apoptosis and plays a particularly critical role in pancreatic β-cell biology and diabetes development. High glucose and diabetes induce TXNIP expression, w...

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Autores principales: Chen, Junqin, Jing, Gu, Xu, Guanlan, Shalev, Anath
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2014
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004782/
https://ncbi.nlm.nih.gov/pubmed/24628418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1041
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