FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells

Thioredoxin-interacting protein (TXNIP) has emerged as an important factor in pancreatic beta cell biology, and tight regulation of TXNIP levels is necessary for beta cell survival. However, the mechanisms regulating TXNIP expression have only started to be elucidated. The forkhead boxO1 transcripti...

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Detaylı Bibliyografya
Asıl Yazarlar: Kibbe, Carly, Chen, Junqin, Xu, Guanlan, Jing, Gu, Shalev, Anath
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743491/
https://ncbi.nlm.nih.gov/pubmed/23803610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473082
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