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FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells

Thioredoxin-interacting protein (TXNIP) has emerged as an important factor in pancreatic beta cell biology, and tight regulation of TXNIP levels is necessary for beta cell survival. However, the mechanisms regulating TXNIP expression have only started to be elucidated. The forkhead boxO1 transcripti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kibbe, Carly, Chen, Junqin, Xu, Guanlan, Jing, Gu, Shalev, Anath
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743491/
https://ncbi.nlm.nih.gov/pubmed/23803610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473082
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