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FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells

Thioredoxin-interacting protein (TXNIP) has emerged as an important factor in pancreatic beta cell biology, and tight regulation of TXNIP levels is necessary for beta cell survival. However, the mechanisms regulating TXNIP expression have only started to be elucidated. The forkhead boxO1 transcripti...

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Hlavní autoři: Kibbe, Carly, Chen, Junqin, Xu, Guanlan, Jing, Gu, Shalev, Anath
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743491/
https://ncbi.nlm.nih.gov/pubmed/23803610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473082
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