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The Deubiquitinase USP28 Stabilizes LSD1 and Confers Stem-cell-like Traits to Breast Cancer Cells
LSD1 is a critical chromatin modulator controlling cellular pluripotency and differentiation through the demethylation of H3K4me1/2. Overexpression of LSD1 has been observed in many types of tumors and is correlated with its oncogenic effects in tumorigenesis. However, the mechanism leading to LSD1...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004762/ https://ncbi.nlm.nih.gov/pubmed/24075993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.030 |
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