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DREADDs: novel tools for drug discovery and development

Since the invention of the first designer receptors exclusively activated by designer drugs (DREADDs), these engineered G protein-coupled receptors (GPCRs) have been widely applied in investigations of biological processes and behaviors. DREADD technology has emerged as a powerful tool with great po...

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Bibliographic Details
Main Authors: Lee, Hyeong-Min, Giguere, Patrick M., Roth, Bryan L.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004703/
https://ncbi.nlm.nih.gov/pubmed/24184433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.10.018
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