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CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells
BACKGROUND: Radioresistance in human tumors has been linked in part to a subset of cells termed cancer stem cells (CSCs). The prominin 1 (CD133) cell surface protein is proposed to be a marker enriching for CSCs. We explore the importance of DNA repair in contributing to radioresistance in CD133+ lu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004669/ https://ncbi.nlm.nih.gov/pubmed/24440048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2013.10.040 |
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