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The DNA repair function of CUX1 contributes to radioresistance

Ionizing radiation generates a broad spectrum of oxidative DNA lesions, including oxidized base products, abasic sites, single-strand breaks and double-strand breaks. The CUX1 protein was recently shown to function as an auxiliary factor that stimulates enzymatic activities of OGG1 through its CUT d...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Ramdzan, Zubaidah M., Ginjala, Vasudeva, Pinder, Jordan B., Chung, Dudley, Donovan, Caroline M., Kaur, Simran, Leduy, Lam, Dellaire, Graham, Ganesan, Shridar, Nepveu, Alain
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386666/
https://ncbi.nlm.nih.gov/pubmed/28147323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14875
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