RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage

The Cut homeobox 1 (CUX1) gene is a target of loss-of-heterozygosity in many cancers, yet elevated CUX1 expression is frequently observed and is associated with shorter disease-free survival. The dual role of CUX1 in cancer is illustrated by the fact that most cell lines with CUX1 LOH display amplif...

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Detalhes bibliográficos
Main Authors: Ramdzan, Zubaidah M., Vadnais, Charles, Pal, Ranjana, Vandal, Guillaume, Cadieux, Chantal, Leduy, Lam, Davoudi, Sayeh, Hulea, Laura, Yao, Lu, Karnezis, Anthony N., Paquet, Marilène, Dankort, David, Nepveu, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949673/
https://ncbi.nlm.nih.gov/pubmed/24618719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001807
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