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Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer
Lung cancer evades host immune surveillance by dysregulating inflammation. Tumors and their surrounding stromata produce growth factors, cytokines, and chemokines that recruit, expand, and/or activate myeloid-derived suppressor cells (MDSCs). MDSCs regulate immune responses and are frequently found...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004632/ https://ncbi.nlm.nih.gov/pubmed/24791250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S32617 |
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