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Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer

Lung cancer evades host immune surveillance by dysregulating inflammation. Tumors and their surrounding stromata produce growth factors, cytokines, and chemokines that recruit, expand, and/or activate myeloid-derived suppressor cells (MDSCs). MDSCs regulate immune responses and are frequently found...

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Hlavní autoři: Srivastava, Minu K, Zhu, Li, Harris-White, Marni, Huang, Min, St John, Maie, Lee, Jay M, Salgia, Ravi, Cameron, Robert B, Strieter, Robert, Dubinett, Steven, Sharma, Sherven
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004632/
https://ncbi.nlm.nih.gov/pubmed/24791250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S32617
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