Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer

Lung cancer evades host immune surveillance by dysregulating inflammation. Tumors and their surrounding stromata produce growth factors, cytokines, and chemokines that recruit, expand, and/or activate myeloid-derived suppressor cells (MDSCs). MDSCs regulate immune responses and are frequently found...

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Autors principals: Srivastava, Minu K, Zhu, Li, Harris-White, Marni, Huang, Min, St John, Maie, Lee, Jay M, Salgia, Ravi, Cameron, Robert B, Strieter, Robert, Dubinett, Steven, Sharma, Sherven
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004632/
https://ncbi.nlm.nih.gov/pubmed/24791250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S32617
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