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A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype

Pituitary adenomas (PAs) are neoplasms that may cause a variety of neurological and endocrine effects. Although known causal contributors include heredity, hormonal influence and somatic mutations, the pathophysiologic mechanisms driving tumorigenesis and invasion of sporadic PAs remain unknown. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ling, Chao, Pease, Matthew, Shi, Lingling, Punj, Vasu, Shiroishi, Mark S., Commins, Deborah, Weisenberger, Daniel J., Wang, Kai, Zada, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004564/
https://ncbi.nlm.nih.gov/pubmed/24781529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096178
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