A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype

Pituitary adenomas (PAs) are neoplasms that may cause a variety of neurological and endocrine effects. Although known causal contributors include heredity, hormonal influence and somatic mutations, the pathophysiologic mechanisms driving tumorigenesis and invasion of sporadic PAs remain unknown. We...

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Библиографические подробности
Главные авторы: Ling, Chao, Pease, Matthew, Shi, Lingling, Punj, Vasu, Shiroishi, Mark S., Commins, Deborah, Weisenberger, Daniel J., Wang, Kai, Zada, Gabriel
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004564/
https://ncbi.nlm.nih.gov/pubmed/24781529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096178
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