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The Role of Epigenetic Modification in Tumorigenesis and Progression of Pituitary Adenomas: A Systematic Review of the Literature

BACKGROUND: Pituitary adenomas (PAs) are commonly occurring neoplasms with diverse endocrine and neurological effects. Although somatic gene mutations are uncommon in sporadic PAs, recent studies lend support to epigenetic modification as a potential cause of tumorigenesis and tumor progression. MET...

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Detalhes bibliográficos
Main Authors: Pease, Matthew, Ling, Chao, Mack, William J., Wang, Kai, Zada, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867353/
https://ncbi.nlm.nih.gov/pubmed/24367530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082619
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