Sequential Activation of Phosphatidylinositol 3-Kinase, βPix, Rac1, and Nox1 in Growth Factor-Induced Production of H(2)O(2)

The generation of reactive oxygen species (ROS) in cells stimulated with growth factors requires the activation of phosphatidylinositol 3-kinase (PI3K) and the Rac protein. We report here that the COOH-terminal region of Nox1, a protein related to gp91(phox) (Nox2) of phagocytic cells, is constituti...

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Detalhes bibliográficos
Main Authors: Park, Hye Sun, Lee, Seung Hye, Park, Dongeun, Lee, Jun Sung, Ryu, Sung Ho, Lee, Won Jae, Rhee, Sue Goo, Bae, Yun Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400450/
https://ncbi.nlm.nih.gov/pubmed/15121857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4384-4394.2004
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