Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake

AIM: Little is known regarding the steady-state uptake of drugs into the human myocardium. Perhexiline is a prophylactic anti-anginal drug which is increasingly also used in the treatment of heart failure and hypertrophic cardiomyopathy. We explored the relationship between plasma perhexiline concen...

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Bibliografske podrobnosti
Main Authors: Drury, Nigel E, Licari, Giovanni, Chong, Cher-Rin, Howell, Neil J, Frenneaux, Michael P, Horowitz, John D, Pagano, Domenico, Sallustio, Benedetta C
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004399/
https://ncbi.nlm.nih.gov/pubmed/24117487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12254
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