The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial

OBJECTIVES: Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients under...

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Veröffentlicht in:Eur J Cardiothorac Surg
Hauptverfasser: Drury, Nigel E., Howell, Neil J., Calvert, Melanie J., Weber, Ralf J.M., Senanayake, Eshan L., Lewis, Michael E., Hyde, Jonathan A.J., Green, David H., Mascaro, Jorge G., Wilson, Ian C., Graham, Timothy R., Rooney, Stephen J., Viant, Mark R., Freemantle, Nick, Frenneaux, Michael P., Pagano, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Adult Cardiac
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324609/
https://ncbi.nlm.nih.gov/pubmed/24948413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ejcts/ezu238
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