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The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia

AIMS: CYP2D6 protein expression is determined by the number of functional CYP2D6 alleles. It is also higher in individuals with at least one CYP2D6*2 allele. This study has investigated the effect of the number of functional CYP2D6 alleles and the influence of CYP2D6*2 alleles on plasma perhexiline...

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Hlavní autoři: Davies, Benjamin J, Coller, Janet K, James, Heather M, Somogyi, Andrew A, Horowitz, John D, Sallustio, Benedetta C
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885028/
https://ncbi.nlm.nih.gov/pubmed/16487226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02570.x
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