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Association between CYP2C19 genotype and proguanil oxidative polymorphism

Aims To examine the relationship between proguanil metabolism and the number of mutations in CYP2C19 by comparing the CYP2C19 genotype and proguanil phenotype of 10 subjects. Methods Partial clearance and urinary metabolic ratio data were obtained from a previous study of 10 subjects [ 5]. Analysis...

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Bibliografiske detaljer
Main Authors: Coller, J. K., Somogyi, A. A., Bochner, F.
Format: Artigo
Sprog:Inglês
Udgivet: Wiley-Blackwell 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042790/
https://ncbi.nlm.nih.gov/pubmed/9205829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00596.x
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