The Glutamate Release Inhibitor Riluzole Decreases Migration, Invasion and Proliferation of Melanoma Cells

The goal of this study was to examine the effects of GRM1 blockade on melanoma anchorage independent growth and invasion. We performed colony and invasion assays using GRM1-expressing melanoma lines and the GRM1 negative UACC930 line. Using the glutamate-release inhibitor Riluzole or the noncompetit...

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Hlavní autoři: Le, Maithao N., Chan, Joseph L.-K., Rosenberg, Stephen A., Nabatian, Adam S., Merrigan, Kim T., Cohen-Solal, Karine A., Goydos, James S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004181/
https://ncbi.nlm.nih.gov/pubmed/20505744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.126
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