A Phase 0 Trial of Riluzole in Patients with Resectable Stage III and IV Melanoma

PURPOSE: Ectopic expression of GRM1 in murine melanocytes results in transformation into a form of melanoma, and more than 60% of human melanoma samples tested ectopically express GRM1. Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase...

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Bibliografiske detaljer
Main Authors: Yip, Dana, Le, Maithao N., Chan, Joseph L.-K., Lee, Jonathan H., Mehnert, Janice A., Yudd, Anthony, Kempf, Jeffery, Shih, Weichung J., Chen, Suzie, Goydos, James S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812866/
https://ncbi.nlm.nih.gov/pubmed/19458050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3303
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