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The microtubule cytoskeleton is required for a G2 cell cycle delay in cancer cells lacking stathmin and p53
In several cancer cell lines, depleting the microtubule-destabilizing protein stathmin/oncoprotein18 leads to a G2 cell cycle delay and apoptosis. These phenotypes are observed only in synergy with low levels of p53, but the pathway(s) activated by stathmin depletion to delay the cell cycle are unkn...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004097/ https://ncbi.nlm.nih.gov/pubmed/22407961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21024 |
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