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Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS). In aged subjects, mitochondria...

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Bibliografiske detaljer
Main Authors: Chistiakov, Dimitry A., Sobenin, Igor A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003832/
https://ncbi.nlm.nih.gov/pubmed/24818134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/238463
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