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Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS). In aged subjects, mitochondria...

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Detalhes bibliográficos
Main Authors: Chistiakov, Dimitry A., Sobenin, Igor A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003832/
https://ncbi.nlm.nih.gov/pubmed/24818134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/238463
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