Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS). In aged subjects, mitochondria...

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Autores principales: Chistiakov, Dimitry A., Sobenin, Igor A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003832/
https://ncbi.nlm.nih.gov/pubmed/24818134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/238463
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