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NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites

The α7 nicotinic acetylcholine receptor (nAChR), assembled as homomeric pentameric ligand-gated ion channels, is one of the most abundant nAChR subtypes in the brain. Despite its importance in memory, learning and cognition, no structure has been determined for the α7 nAChR TM domain, a target for a...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bondarenko, Vasyl, Mowrey, David D., Tillman, Tommy S., Seyoum, Edom, Xu, Yan, Tang, Pei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003566/
https://ncbi.nlm.nih.gov/pubmed/24384062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.12.018
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