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NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites
The α7 nicotinic acetylcholine receptor (nAChR), assembled as homomeric pentameric ligand-gated ion channels, is one of the most abundant nAChR subtypes in the brain. Despite its importance in memory, learning and cognition, no structure has been determined for the α7 nAChR TM domain, a target for a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003566/ https://ncbi.nlm.nih.gov/pubmed/24384062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.12.018 |
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