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NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR
The α4β2 nicotinic acetylcholine receptor (nAChR) has significant roles in nervous system function and disease. It is also a molecular target of general anesthetics. Anesthetics inhibit the α4β2 nAChR at clinically relevant concentrations, but their binding sites in α4β2 remain unclear. The recently...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534943/ https://ncbi.nlm.nih.gov/pubmed/23000369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.09.014 |
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