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Aminobutyric Acid Type A Receptor β3 Subunit Forebrain-Specific Knockout Mice Are Resistant to the Amnestic Effect of Isoflurane
BACKGROUND: β3 containing γ–aminobutyric acid type A receptors (GABA(A)-Rs) mediate behavioral end points of IV anesthetics such as immobility and hypnosis. A knockout mouse with targeted forebrain deletion of the β3 subunit of the GABA(A)-R shows reduced sensitivity to the hypnotic effect of etomid...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003562/ https://ncbi.nlm.nih.gov/pubmed/21813630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182273aff |
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