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Knockout of the gene encoding the K(2P) channel KCNK7 does not alter volatile anesthetic sensitivity

The molecular site of action for volatile anesthetics remains unknown despite many years of study. Members of the K(2P) potassium channel family, whose currents are potentiated by volatile anesthetics have emerged as possible anesthetic targets. In fact, a mouse model in which the gene for TREK-1 (K...

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Detalhes bibliográficos
Main Authors: Yost, C. Spencer, Oh, Irene, Eger, Edmond I., Sonner, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669440/
https://ncbi.nlm.nih.gov/pubmed/18572259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2008.05.010
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