The V1/V2 Domain of gp120 Is a Global Regulator of the Sensitivity of Primary Human Immunodeficiency Virus Type 1 Isolates to Neutralization by Antibodies Commonly Induced upon Infection

A major problem hampering the development of an effective vaccine against human immunodeficiency virus type 1 (HIV-1) is the resistance of many primary viral isolates to antibody-mediated neutralization. To identify factors responsible for this resistance, determinants of the large differences in ne...

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Hlavní autoři: Pinter, Abraham, Honnen, William J., He, Yuxian, Gorny, Miroslaw K., Zolla-Pazner, Susan, Kayman, Samuel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC400352/
https://ncbi.nlm.nih.gov/pubmed/15113902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5205-5215.2004
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