Effect of Soluble CD4 on Exposure of Epitopes on Primary, Intact, Native Human Immunodeficiency Virus Type 1 Virions of Different Genetic Clades

We have used a virus-binding assay to examine conformational changes that occur when soluble CD4 (sCD4) binds to the surface of intact, native, primary human immunodeficiency virus type 1 virions. The isolates examined belong to seven genetic clades (A to H) and are representative of syncytium-induc...

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Detalhes bibliográficos
Main Authors: Mbah, Henry A., Burda, Sherri, Gorny, Miroslaw K., Williams, Constance, Revesz, Kathy, Zolla-Pazner, Susan, Nyambi, Phillipe N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115019/
https://ncbi.nlm.nih.gov/pubmed/11462056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7785-7788.2001
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