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Effect of Soluble CD4 on Exposure of Epitopes on Primary, Intact, Native Human Immunodeficiency Virus Type 1 Virions of Different Genetic Clades

We have used a virus-binding assay to examine conformational changes that occur when soluble CD4 (sCD4) binds to the surface of intact, native, primary human immunodeficiency virus type 1 virions. The isolates examined belong to seven genetic clades (A to H) and are representative of syncytium-induc...

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Udgivet i:J Virol
Principais autores: Mbah, Henry A., Burda, Sherri, Gorny, Miroslaw K., Williams, Constance, Revesz, Kathy, Zolla-Pazner, Susan, Nyambi, Phillipe N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115019/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7785-7788.2001
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