The V3 Loop Is Accessible on the Surface of Most Human Immunodeficiency Virus Type 1 Primary Isolates and Serves as a Neutralization Epitope

Antibodies (Abs) against the V3 loop of the human immunodeficiency virus type 1 gp120 envelope glycoprotein were initially considered to mediate only type-specific neutralization of T-cell-line-adapted viruses. However, recent data show that cross-neutralizing V3 Abs also exist, and primary isolates...

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Hlavní autoři: Gorny, Miroslaw K., Revesz, Kathy, Williams, Constance, Volsky, Barbara, Louder, Mark K., Anyangwe, Christopher A., Krachmarov, Chavdar, Kayman, Samuel C., Pinter, Abraham, Nadas, Arthur, Nyambi, Phillipe N., Mascola, John R., Zolla-Pazner, Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369230/
https://ncbi.nlm.nih.gov/pubmed/14963135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2394-2404.2004
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