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Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e

40S ribosomes are loaded onto capped mRNAs via the multisubunit translation initiation factors eIF3 and eIF4F. While eIF4E is the eIF4F cap recognition component, the eIF4G subunit associates with 40S-bound eIF3. How this intricate process is coordinated remains poorly understood. Here, we identify...

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Detalhes bibliográficos
Main Authors: Walsh, Derek, Mohr, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003276/
https://ncbi.nlm.nih.gov/pubmed/24736843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.236752.113
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