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A novel T cell-based vaccine capable of stimulating long-term functional CTL memory against B16 melanoma via CD40L signaling

The ultimate goal of antitumor vaccines is to develop memory CD8(+) cytotoxic T lymphocytes (CTLs), which are critical mediators of antitumor immunity. We previously demonstrated that the ovalbumin (OVA)-specific CD4(+) T cell-based (OVA-T(EXO)) vaccine generated using OVA-pulsed dendritic cell (DC(...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xie, Yufeng, Wang, Lu, Freywald, Andrew, Qureshi, Mabood, Chen, Yue, Xiang, Jim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003169/
https://ncbi.nlm.nih.gov/pubmed/23042534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.37
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