β-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism

AIM: The role of CYP1A in the protection of aristolochic acid (AA)I-induced nephrotoxicity has been suggested. In the present study we investigated the effects of β-naphthoflavone (BNF), a non-carcinogen CYP1A inducer, on AAI-induced kidney injury. METHODS: Mice were pretreated with 80 mg/kg BNF by...

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Bibliografski detalji
Glavni autori: Xiao, Ying, Xue, Xiang, Wu, Yuan-feng, Xin, Guo-zheng, Qian, Yong, Xie, Tian-pei, Gong, Li-kun, Ren, Jin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003015/
https://ncbi.nlm.nih.gov/pubmed/19890363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.156
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