Involvement of cytochrome P450 3A4 and P-glycoprotein in first-pass intestinal extraction of omeprazole in rabbits

AIM: To quantitatively evaluate in vivo first-pass intestinal extraction of omeprazole and to investigate the possible involvement of cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in this process in rabbits. METHODS: Pharmacokinetic parameters were examined after intraduodenal (id), intrapo...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Fang, Hai-ming, Xu, Jian-ming, Mei, Qiao, Diao, Lei, Chen, Mo-li, Jin, Juan, Xu, Xin-hua
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
主題:
Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003004/
https://ncbi.nlm.nih.gov/pubmed/19820718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.142
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍