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Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice
AIM: To investigate the effects of ATPM-ET [(−)-3-N-Ethylaminothiazolo [5,4-b]-N-cyclopropylmethylmorphinan hydrochloride] on physical dependence and behavioral sensitization to morphine in mice. METHODS: The pharmacological profile of ATPM-ET was characterized using competitive binding and GTPγS bi...
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Главные авторы: | , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Nature Publishing Group
2010
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002947/ https://ncbi.nlm.nih.gov/pubmed/21102484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.164 |
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