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Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice

AIM: To investigate the effects of ATPM-ET [(−)-3-N-Ethylaminothiazolo [5,4-b]-N-cyclopropylmethylmorphinan hydrochloride] on physical dependence and behavioral sensitization to morphine in mice. METHODS: The pharmacological profile of ATPM-ET was characterized using competitive binding and GTPγS bi...

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Библиографические подробности
Главные авторы: Sun, Jian-feng, Wang, Yu-hua, Li, Fu-ying, Lu, Gang, Tao, Yi-min, Cheng, Yun, Chen, Jie, Xu, Xue-jun, Chi, Zhi-qiang, Neumeyer, John L, Zhang, Ao, Liu, Jing-gen
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002947/
https://ncbi.nlm.nih.gov/pubmed/21102484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.164
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