Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation

AIM: To examine the effects of pioglitazone, a PPARγ agonist, on memory performance and brain amyloidogenesis in streptozotocin (STZ)-induced diabetic mice. METHODS: ICR male mice were injected with STZ (150 mg/kg, iv) to induce experimental diabetes. Pioglitazone (9 and 18 mg·kg(-1)·d(-1), po) was...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Li-ping, Yan, Tian-hua, Jiang, Li-ying, Hu, Wei, Hu, Meng, Wang, Chao, Zhang, Qian, Long, Yan, Wang, Jiang-qing, Li, Yong-qi, Hu, Mei, Hong, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002797/
https://ncbi.nlm.nih.gov/pubmed/23524568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados