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Generation and characterization of the human neutralizing antibody fragment Fab091 against rabies virus

AIM: To transform the human anti-rabies virus glycoprotein (anti-RABVG) single-chain variable fragment (scFv) into a Fab fragment and to analyze its immunological activity. METHODS: The Fab gene was amplified using overlap PCR and inserted into the vector pComb3XSS. The recombinant vector was then t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Li, Chen, Zhang, Feng, Lin, Hong, Wang, Zhong-can, Liu, Xin-jian, Feng, Zhen-qing, Zhu, Jin, Guan, Xiao-hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002766/
https://ncbi.nlm.nih.gov/pubmed/21278782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.209
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