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Generation of a Neutralizing Human Monoclonal Antibody Fab Fragment to Surface Antigen 1 of Toxoplasma gondii Tachyzoites

A combinatorial immunoglobulin gene library was constructed from lymphocytes in peripheral blood of a patient with toxoplasmosis and screened for production of human monoclonal antibody Fab fragments to recombinant surface antigen 1 (SAG1) of Toxoplasma gondii. Two Fab clones, Tox203 and Tox1403, wh...

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Detalhes bibliográficos
Main Authors: Fu, Yong-Feng, Feng, Meng, Ohnishi, Kenji, Kimura, Tamon, Itoh, Johbu, Cheng, Xun-Jia, Tachibana, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019919/
https://ncbi.nlm.nih.gov/pubmed/20956568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00969-10
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