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Toll-like receptor 3 agonist Poly I:C protects against simulated cerebral ischemia in vitro and in vivo
AIM: To examine the neuroprotective effects of the Toll-like receptor 3 (TLR3) agonist Poly I:C in acute ischemic models in vitro and in vivo. METHODS: Primary astrocyte cultures subjected to oxygen-glucose deprivation (OGD) were used as an in vitro simulated ischemic model. Poly I:C was administrat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002702/ https://ncbi.nlm.nih.gov/pubmed/22983393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.122 |
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