Toll-like receptor 3 agonist Poly I:C protects against simulated cerebral ischemia in vitro and in vivo

AIM: To examine the neuroprotective effects of the Toll-like receptor 3 (TLR3) agonist Poly I:C in acute ischemic models in vitro and in vivo. METHODS: Primary astrocyte cultures subjected to oxygen-glucose deprivation (OGD) were used as an in vitro simulated ischemic model. Poly I:C was administrat...

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Detalhes bibliográficos
Main Authors: Pan, Lin-na, Zhu, Wei, Li, Cai, Xu, Xu-lin, Guo, Lian-jun, Lu, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002702/
https://ncbi.nlm.nih.gov/pubmed/22983393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.122
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