Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress

AIM: Proteasome inhibitors have been found to suppress glioma cell proliferation and induce apoptosis, but the mechanisms are not fully elucidated. In this study we investigated the mechanisms underlying the apoptosis induced by the proteasome inhibitor MG-132 in glioma cells. METHODS: C6 glioma cel...

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Bibliografiske detaljer
Main Authors: Fan, Wen-hai, Hou, Yi, Meng, Fan-kai, Wang, Xiao-fei, Luo, Yi-nan, Ge, Peng-fei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002511/
https://ncbi.nlm.nih.gov/pubmed/21499287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.16
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