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Combination of Proteasomal Inhibitors Lactacystin and MG132 Induced Synergistic Apoptosis in Prostate Cancer Cells

The proteasome inhibitor Velcade (bortezomib/PS-341) has been shown to block the targeted proteolytic degradation of short-lived proteins that are involved in cell maintenance, growth, division, and death, advocating the use of proteasomal inhibitors as therapeutic agents. Although many studies focu...

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Hlavní autoři: Shirley, Robert B, Kaddour-Djebbar, Ismail, Patel, Dimpu M, Lakshmikanthan, Vijayabaskar, Lewis, Ronald W, Kumar, M Vijay
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501172/
https://ncbi.nlm.nih.gov/pubmed/16354593
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