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The proteasomal inhibitor MG132 prevents muscular dystrophy in zebrafish

Using sapje zebrafish which lack dystrophin, we have assessed both the quantitation of muscle damage in dystrophic fish, and the efficacy of the proteasomal inhibitor MG132 in reducing the dystrophic symptoms. Fourier analysis of birefringence patterns in normal and dystrophic fish was found to be a...

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Hlavní autoři: Winder, Steve J, Lipscomb, Leanne, Angela Parkin, Caroline, Juusola, Mikko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219425/
https://ncbi.nlm.nih.gov/pubmed/22130468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1286
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