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The proteasomal inhibitor MG132 prevents muscular dystrophy in zebrafish

Using sapje zebrafish which lack dystrophin, we have assessed both the quantitation of muscle damage in dystrophic fish, and the efficacy of the proteasomal inhibitor MG132 in reducing the dystrophic symptoms. Fourier analysis of birefringence patterns in normal and dystrophic fish was found to be a...

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Detalles Bibliográficos
Main Authors: Winder, Steve J, Lipscomb, Leanne, Angela Parkin, Caroline, Juusola, Mikko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219425/
https://ncbi.nlm.nih.gov/pubmed/22130468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1286
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