Design, synthesis and biological evaluation of bivalent ligands against A(1)–D(1) receptor heteromers

AIM: To design and synthesize bivalent ligands for adenosine A(1)–dopamine D(1) receptor heteromers (A(1)–D(1)R), and evaluate their pharmacological activities. METHODS: Bivalent ligands and their corresponding A(1)R monovalent ligands were designed and synthesized. The affinities of the bivalent li...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shen, Jian, Zhang, Lei, Song, Wan-ling, Meng, Tao, Wang, Xin, Chen, Lin, Feng, Lin-yin, Xu, Ye-chun, Shen, Jing-kang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002486/
https://ncbi.nlm.nih.gov/pubmed/23334237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.151
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados