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Design, synthesis and biological evaluation of bivalent ligands against A(1)–D(1) receptor heteromers
AIM: To design and synthesize bivalent ligands for adenosine A(1)–dopamine D(1) receptor heteromers (A(1)–D(1)R), and evaluate their pharmacological activities. METHODS: Bivalent ligands and their corresponding A(1)R monovalent ligands were designed and synthesized. The affinities of the bivalent li...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002486/ https://ncbi.nlm.nih.gov/pubmed/23334237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.151 |
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