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Type I and II interferons enhance dendritic cell maturation and migration capacity by regulating CD38 and CD74 that have synergistic effects with TLR agonists

The major limitation for the maturation of dendritic cells (DCs) using Toll-like receptor (TLR) agonists is their decreased ability to migrate into lymph nodes compared with conventional DCs. CD38 can be used as a multifunctional marker to modulate migration, survival and Th1 responses of DCs. CD74...

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Detalhes bibliográficos
Main Authors: Nguyen-Pham, Thanh-Nhan, Lim, Mi-Seon, Nguyen, Truc Anh Thi, Lee, Youn-Kyung, Jin, Chun-Ji, Lee, Hyun Ju, Hong, Cheol Yi, Ahn, Jae-Sook, Yang, Deok-Hwan, Kim, Yeo-Kyeoung, Chung, Ik-Joo, Park, Byoung Chul, Kim, Hyeoung-Joon, Lee, Je-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002448/
https://ncbi.nlm.nih.gov/pubmed/21423200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.7
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