Transforming growth factor-β1 upregulates the expression of CXC chemokine receptor 4 (CXCR4) in human breast cancer MCF-7 cells

AIM: To investigate whether rhTGF-β1 or a recombinant vector encoding a fusion protein comprising an extracellular domain of TGF-β receptor II and an IgG Fc fragment) affects the regulation of CXC chemokine receptor 4 (CXCR4) expression in MCF-7 human breast cancer cells. METHODS: MCF-7 breast cance...

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Main Authors: Zhao, Xiao-ping, Huang, Yong-yao, Huang, Yu, Lei, Ping, Peng, Ji-lin, Wu, Sha, Wang, Min, Li, Wen-han, Zhu, Hui-fen, Shen, Guan-xin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002409/
https://ncbi.nlm.nih.gov/pubmed/20154716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.204
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